the gateway to suprachoroidal drug delivery
Bella-vue | the suprachoroidal needle
Bella-vue is U-Needle's silicon microneedle for the delivery of drugs to the suprachoroidal space. Various evaluation studies in animal models such as rabbits, pigs and nonhuman primates have demonstrated safe en effective delivery of compounds to the back of the eye with Bella-vue.
Currently U-Needle is teaming up with pharmaceutical partners developing various therapies for major retinal diseases.
Please contact us to discuss the use of the Bella-vue silicon microneedle for the suprachoroidal delivery of your therapy.
The suprachoroidal space, between the sclera and the choroid, spans the whole back of the eye and somewhat extends to the front. It can be conveniently accessed with a microneedle of the appropriate length. Fluids injected into the suprachoroidal space in the front part of the eye (4-5mm backward from the Limbus) will spread throughout the space. This enables targeted drug delivery to the choroid and the retina.
Advantages of the Bella-vue suprachoroidal needle
Suprachoroidal injections enable access to the back of the eye as fluid spreads posteriorly from the injection site in a circumferential manner. Providing excellent bioavailabillty of therapeutic formulations.
Due to the small bevel size of the Bella-vue needle, the injection depth is consistent and precise.
The Bella-vue is a high-tech solution disguised as an ordinary hypodermic needle. Its design facilitates a perpendicular injection and it can be attached to any Luer-lock syringe. Thereby allowing usability in an in-office setting.