Intradermal Injection | Perpendicular Injection with a Silicon Microneedle
Intradermal drug delivery
The intradermal route of administration offers several therapeutic benefits:
Effective targeting of the immune system
Direct access to the skin
Fast systemic uptake
Given the above, intradermal injection is emerging as the preferred route of administration for many innovative therapies. However, the standard-of-care method for intradermal injection, the almost a century old "Mantoux technique" performed with an ordinary hypodermic needle, is complex and unreliable. Recent scientific literature suggests that about 70% of the intradermal injections performed with the Mantoux technique fail and actually end up in the hypodermis. Hereby, the Mantoux technique impedes pharmaceutical innovation and there is a clear and urgent need for an easy-to-use but reliable intradermal injection method.
Uneedle's silicon microneedle technology allows for perpendicular injection, an innovative approach to intradermal injection which is reliable and easy to perform. The microneedle is fully inserted until the hub loosely touches the surface of the skin and and then the fluid is simply injected at a controlled depth of about 1 mm. The result is a clearly visible bleb/wheal on the skin, which is the hallmark of a successful intradermal injection.
Last but not least, due to the extreme small size and super sharp tip of our microneedles, needle fear and pain are strongly reduced.